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DP-IACS
Dislipemias primarias
Instituto Aragonés de Ciencias de la Salud, Hospital Miguel Servet. Zaragoza
- de Gonzalo-Calvo D, Cenarro A, Martínez-Bujidos M, Badimon L, Bayés-Genís A, Ordonez-Llanos J, Civeira F, Llorente-Cortés V Circulating soluble low-density lipoprotein receptor-related protein 1 (sLRP1) concentration is associated with hypercholesterolemia: A new potential biomarker for atherosclerosis. Int. J. Cardiol. 2015; 201: 20-9
- Ledesma M, Hurtado-Roca Y, León M, Giraldo P, Pocoví M, Civeira F, Guallar E, Ordovas JM, Casasnovas JA, Laclaustra M Association of ferritin elevation and metabolic syndrome in males. Results from the Aragon Workers' Health Study (AWHS). J. Clin. Endocrinol. Metab. 2015; 100: 2081-9
- Saravia G, Civeira F, Hurtado-Roca Y, Andrés E, León M, Pocoví M, Ordovas J, Guallar E, Fernández-Ortiz A, Casasnovas JA, Laclaustra M Glycated Hemoglobin, Fasting Insulin and the Metabolic Syndrome in Males. Cross-Sectional Analyses of the Aragon Workers' Health Study Baseline. PLoS ONE 2015; 10: e0132244
- Baila-Rueda L, Mateo-Gallego R, Perez-Calahorra S, Lamiquiz-Moneo I, De Castro-Orós I, Cenarro A, Civeira F Effect of different fat-enriched meats on non-cholesterol sterols and oxysterols as markers of cholesterol metabolism: Results of a randomized and cross-over clinical trial. Nutr Metab Cardiovasc Dis 2015; 25: 853-9
- Kastelein JJ, Ginsberg HN, Langslet G, Hovingh GK, Ceska R, Dufour R, Blom D, Civeira F, Krempf M, Lorenzato C, Zhao J, Pordy R, Baccara-Dinet MT, Gipe DA, Geiger MJ, Farnier M ODYSSEY FH I and FH II: 78 week results with alirocumab treatment in 735 patients with heterozygous familial hypercholesterolaemia. Eur. Heart J. 2015; 36: 2996-3003
- Sotos-Prieto M, Moreno-Franco B, Ordovas JM, León M, Casasnovas JA, Peñalvo JL Design and development of an instrument to measure overall lifestyle habits for epidemiological research: the Mediterranean Lifestyle (MEDLIFE) index. Public Health Nutr 2015; 18: 959-67
- Ascaso JF, Mata P, Arbona C, Civeira F, Valdivielso P, Masana L [Homozygous familial hypercholesterolaemia: Spanish adaptation of the position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society. Consensus document of the Spanish Society of Arteriosclerosis (SEA) and Familial Hypercholesterolaemia Foundation (FHF)]. Clin Investig Arterioscler 2015; 27: 80-96
- Guardiola M, Cofán M, De Castro-Orós I, Cenarro A, Plana N, Talmud PJ, Masana L, Ros E, Civeira F, Ribalta J APOA5 variants predispose hyperlipidemic patients to atherogenic dyslipidemia and subclinical atherosclerosis. Atherosclerosis 2015; 240: 98-104
- Versmissen J, Oosterveer DM, Yazdanpanah M, Dehghan A, Hólm H, Erdman J, Aulchenko YS, Thorleifsson G, Schunkert H, Huijgen R, Vongpromek R, Uitterlinden AG, Defesche JC, van Duijn CM, Mulder M, Dadd T, Karlsson HD, Ordovas J, Kindt I, Jarman A, Hofman A, van Vark-van der Zee L, Blommesteijn-Touw AC, Kwekkeboom J, Liem AH, van der Ouderaa FJ, Calandra S, Bertolini S, Averna M, Langslet G, Ose L, Ros E, Almagro F, de Leeuw PW, Civeira F, Masana L, Pinto X, Simoons ML, Schinkel AF, Green MR, Zwinderman AH, Johnson KJ, Schaefer A, Neil A, Witteman JC, Humphries SE, Kastelein JJ, Sijbrands EJ Identifying genetic risk variants for coronary heart disease in familial hypercholesterolemia: an extreme genetics approach. Eur. J. Hum. Genet. 2015; 23: 381-7
- Mateo-Gallego R, Baila-Rueda L, Mouratidou T, De Castro-Orós I, Bea AM, Perez-Calahorra S, Cenarro A, Moreno LA, Civeira F Serum plant sterols as surrogate markers of dietary compliance in familial dyslipidemias. Clin Nutr 2015; 34: 490-5
- Etxebarria A, Benito-Vicente A, Palacios L, Stef M, Cenarro A, Civeira F, Ostolaza H, Martin C Functional characterization and classification of frequent low-density lipoprotein receptor variants. Hum. Mutat. 2015; 36: 129-41
- Masana L, Pedro-Botet J, Civeira F IMPROVE-IT clinical implications. Should the "high-intensity cholesterol-lowering therapy" strategy replace the "high-intensity statin therapy"? Atherosclerosis 2015; 240: 161-2
- Lamiquiz-Moneo I, Bea AM, Mateo-Gallego R, Baila-Rueda L, Cenarro A, Pocoví M, Civeira F, De Castro-Orós I [Identification of variants in LMF1 gene associated with primary hypertriglyceridemia]. Clin Investig Arterioscler 2015; 27: 246-52
- Raal FJ, Stein EA, Dufour R, Turner T, Civeira F, Burgess L, Langslet G, Scott R, Olsson AG, Sullivan D, Hovingh GK, Cariou B, Gouni-Berthold I, Somaratne R, Bridges I, Wasserman SM, Gaudet D PCSK9 inhibition with evolocumab (AMG 145) in heterozygous familial hypercholesterolaemia (RUTHERFORD-2): a randomised, double-blind, placebo-controlled trial. Lancet 2015; 385: 331-40
- Fernández-Friera L, Peñalvo JL, Fernández-Ortiz A, Ibáñez B, López-Melgar B, Laclaustra M, Oliva B, Mocoroa A, Mendiguren J, Martínez de Vega V, García L, Molina J, Sánchez-González J, Guzmán G, Alonso-Farto JC, Guallar E, Civeira F, Sillesen H, Pocock S, Ordovas JM, Sanz G, Jiménez-Borreguero LJ, Fuster V Prevalence, Vascular Distribution, and Multiterritorial Extent of Subclinical Atherosclerosis in a Middle-Aged Cohort: The PESA (Progression of Early Subclinical Atherosclerosis) Study. Circulation 2015; 131: 2104-13
- De Castro-Orós I, Cenarro A, Tejedor MT, Baila-Rueda L, Mateo-Gallego R, Lamiquiz-Moneo I, Pocoví M, Civeira F Common genetic variants contribute to primary hypertriglyceridemia without differences between familial combined hyperlipidemia and isolated hypertriglyceridemia. Circ Cardiovasc Genet 2014; 7: 814-21
- Baila-Rueda L, Mateo-Gallego R, Lamiquiz-Moneo I, Cenarro A, Civeira F Severe hypercholesterolemia and phytosterolemia with extensive xanthomas in primary biliary cirrhosis: role of biliary excretion on sterol homeostasis. J Clin Lipidol 2014; 8: 520-4
- Cenarro A, Puzo J, Ferrando J, Mateo-Gallego R, Bea AM, Calmarza P, Jarauta E, Civeira F Effect of Nicotinic acid/Laropiprant in the lipoprotein(a) concentration with regard to baseline lipoprotein(a) concentration and LPA genotype. Metab. Clin. Exp. 2014; 63: 365-71
- Merino J, Masana L, Guijarro C, Ascaso J, Lagares M, Civeira F [Recomendations for clinical use of food enriched phytosterols/phytostanols handling hypercholesterolemia]. Clin Investig Arterioscler 2014; 26: 147-58
- Jarauta E, Mateo-Gallego R, Bea AM, Crespo M, Ballester A, Rubio MV, Baila-Rueda L, Calmarza P, Cenarro A, de Groot E, Civeira F Atherosclerosis progression in patients with autosomal dominant hypercholesterolemia in clinical practice. J Clin Lipidol 2014; 8: 373-80
- Koren MJ, Giugliano RP, Raal FJ, Sullivan D, Bolognese M, Langslet G, Civeira F, Somaratne R, Nelson P, Liu T, Scott R, Wasserman SM, Sabatine MS Efficacy and safety of longer-term administration of evolocumab (AMG 145) in patients with hypercholesterolemia: 52-week results from the Open-Label Study of Long-Term Evaluation Against LDL-C (OSLER) randomized trial. Circulation 2014; 129: 234-43
- Baila-Rueda L, Mateo-Gallego R, Jarauta E, De Castro-Orós I, Bea AM, Cenarro A, Civeira F Bile acid synthesis precursors in familial combined hyperlipidemia: the oxysterols 24S-hydroxycholesterol and 27-hydroxycholesterol. Biochem. Biophys. Res. Commun. 2014; 446: 731-5
- Bea AM, Mateo-Gallego R, Jarauta E, Villa-Pobo R, Calmarza P, Lamiquiz-Moneo I, Cenarro A, Civeira F [Lipoprotein(a) is associated to atherosclerosis in primary hypercholesterolemia]. Clin Investig Arterioscler 2014; 26: 176-83
- Stroes E, Colquhoun D, Sullivan D, Civeira F, Rosenson RS, Watts GF, Bruckert E, Cho L, Dent R, Knusel B, Xue A, Scott R, Wasserman SM, Rocco M Anti-PCSK9 antibody effectively lowers cholesterol in patients with statin intolerance: the GAUSS-2 randomized, placebo-controlled phase 3 clinical trial of evolocumab. J. Am. Coll. Cardiol. 2014; 63: 2541-8
- De Castro-Orós I, Pérez-López J, Mateo-Gallego R, Rebollar S, Ledesma M, León M, Cofán M, Casasnovas JA, Ros E, Rodríguez-Rey JC, Civeira F, Pocoví M A genetic variant in the LDLR promoter is responsible for part of the LDL-cholesterol variability in primary hypercholesterolemia. BMC Med Genomics 2014; 7: 17
- Mateo-Gallego R, Perez-Calahorra S, Cofán M, Baila-Rueda L, Cenarro A, Ros E, Puzo J, Civeira F Serum lipid responses to weight loss differ between overweight adults with familial hypercholesterolemia and those with familial combined hyperlipidemia. J. Nutr. 2014; 144: 1219-26
- Silvestre-Roig C, Fernández P, Mansego ML, van Tiel CM, Viana R, Viviani Anselmi C, Anselmi CV, Condorelli G, de Winter RJ, Martín-Fuentes P, Solanas-Barca M, Civeira F, Focaccio A, de Vries CJ, Chaves FJ, Andrés V Genetic variants in CCNB1 associated with differential gene transcription and risk of coronary in-stent restenosis. Circ Cardiovasc Genet 2014; 7: 59-70
- Jorge I, Burillo E, Mesa R, Baila-Rueda L, Moreno M, Trevisan-Herraz M, Silla-Castro JC, Camafeita E, Ortega-Muñoz M, Bonzon-Kulichenko E, Calvo I, Cenarro A, Civeira F, Vázquez J The human HDL proteome displays high inter-individual variability and is altered dynamically in response to angioplasty-induced atheroma plaque rupture. J Proteomics 2014; 106: 61-73
- Tellez-Plaza M, Tang WY, Shang Y, Umans JG, Francesconi KA, Goessler W, Ledesma M, León M, Laclaustra M, Pollak J, Guallar E, Cole SA, Fallin MD, Navas-Acien A Association of global DNA methylation and global DNA hydroxymethylation with metals and other exposures in human blood DNA samples. Environ. Health Perspect. 2014; 122: 946-54
- Calmarza P, Trejo JM, Lapresta C, López P LDL oxidation and its association with carotid artery intima-media thickness and other cardiovascular risk factors in a sample of Spanish general population. Angiology 2014; 65: 357-62
- Pedragosa À, Merino J, Aranda JL, Galiana J, Godoy D, Panisello JM, Ascaso JF, Civeira F, Masana L, Pedro-Botet J [Clinical profile of patients with very high hypertriglyceridemia from the Registry of Hypertriglyceridemia of the Spanish Atherosclerosis Society]. Clin Investig Arterioscler 2013; 25: 8-15
- Sala-Vila A, Cofán M, Mateo-Gallego R, Cenarro A, Civeira F, Ros E Eicosapentaenoic acid in serum phospholipids relates to a less atherogenic lipoprotein profile in subjects with familial hypercholesterolemia. J. Nutr. Biochem. 2013; 24: 1604-8
- Santaló M, Martin A, Velilla J, Povar J, Temboury F, Balaguer J, Muñoz M, Calmarza P, Ortiz C, Carratalá A, Gich I, Mercé J, Jaffe AS, Ordoñez-Llanos J Using high-sensitivity troponin T: the importance of the proper gold standard. Am. J. Med. 2013; 126: 709-17
- Merino J, Mateo-Gallego R, Plana N, Bea AM, Ascaso J, Lahoz C, Aranda JL Low-fat dairy products consumption is associated with lower triglyceride concentrations in a Spanish hypertriglyceridemic cohort. Nutr Hosp 2013; 28: 927-33
- Masana L, Civeira F, Pedro-Botet J, de Castro I, Pocoví M, Plana N, Mateo-Gallego R, Jarauta E, Pedragosa À [Expert consensus on the detection and clinical management of familial hypercholesterolemia]. Clin Investig Arterioscler 2013; 25: 182-93
- Civeira F [Prevention of cardiovascular diseases needs prevention for arteriosclerosis development and its risk factors]. Clin Investig Arterioscler 2013; 25: 110-1
- Civeira F [Message from the chairman. The indexing of Clínica e Investigación en Arteriosclersis; a stimulus and opportunity for all]. Clin Investig Arterioscler 2013; 25: 53
- Calmarza P, Trejo JM, Lapresta C, López P Lack of association between carotid intima-media thickness and apolipoprotein (a) isoforms in a sample of Spanish general population. J Cardiol 2013; 61: 372-7
- Cordero A, Lopez-Palop R, Bertomeu-González V, Carrillo P, Moreno-Arribas J, Bertomeu-Martínez V Clinical Profile and Prognosis of Patients With Low-density Lipoprotein Cholesterol <70mg/dL and Acute Coronary Syndrome. Rev Esp Cardiol (Engl Ed) 2013; 66: 588-9
- Civeira F [Cardiovascular diseases in Spain: conclusions and final comments]. Clin Investig Arterioscler 2013; 25: 231-2
- Mateo-Gallego R, Perez-Calahorra S, Cenarro A, Bea AM, Andrés E, Horno J, Ros E, Civeira F Effect of lean red meat from lamb v. lean white meat from chicken on the serum lipid profile: a randomised, cross-over study in women. Br. J. Nutr. 2012; 107: 1403-7
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