Garcia-Alvarez A, Sitges M, Heras M, Poyatos S, Posada E, Pinazo MJ, Regueiro A, Gascon J, Sanz G
Rev Esp Cardiol. 2011 Oct;64(10):891-6, PMID: 21802190
The number of patients with Chagas disease in Spain has increased significantly. Chronic inflammation and endothelial dysfunction have been considered among the physiopathological mechanisms of Chagas heart disease. However, there have been conflicting data from clinical studies. Our purpose was to assess endothelial function and systemic levels of nitric oxide and high-sensitivity C-reactive protein in patients with the indeterminate form and with chronic Chagas cardiomyopathy living in a nonendemic area.
CARDIAC & CARDIOVASCULAR SYSTEMS