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Cid J, Carbassé G, Pereira A, Sanz C, Mazzara R, Escolar G, Lozano M

Platelet transfusions from D+ donors to D- patients: a 10-year follow-up study of 1014 patients.

Transfusion. 2011 Jun;51(6):1163-9, PMID: 21126258

Current guidelines recommend that platelets (PLTs) from D- donors should be given to D- patients. However, such evidence comes from studies with a limited number of included patients that reported an incidence of anti-D alloimmunization to be up to 19%. We thus decided to extend these findings by examining anti-D alloimmunization at our institution, where PLT transfusions from D+ donors are transfused to D- patients because of logistic constraints.

HEMATOLOGY