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Hermenegildo C, Oviedo PJ, Laguna A, García-Pérez MA, Tarín JJ, Cano A

Transdermal estradiol reduces F2alpha-isoprostane levels in postmenopausal women.

Menopause. 2008;15(4):714-7, PMID: 18340278

F2alpha-isoprostanes are considered the most reliable index of in vivo oxidative stress. Given the implication of oxidative stress in the pathogenesis of atherosclerosis, we investigated the effects of hormone therapy on the plasma levels of F2alpha-isoprostanes.

OBSTETRICS & GYNECOLOGY