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Rigol M, Solanes N, Sionis A, Gálvez C, Martorell J, Rojo I, Brunet M, Ramírez J, Roqué M, Roig E, Pérez-Villa F, Barquín L, Pomar JL, Sanz G, Heras M

Effects of cyclosporine, tacrolimus and sirolimus on vascular changes related to immune response.

J. Heart Lung Transplant.. 2008 Apr;27(4):416-22, PMID: 18374878

Despite the use of newer immunosuppressors such as sirolimus (SRL) and tacrolimus (TRL) in heart transplantation, the rate of humoral rejection has remained unchanged. The aim of this study was to analyze the immunologic and histologic effects of cyclosporine (CsA), SRL, and TRL in a porcine model of arterial transplantation.

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