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Pineda B, Laporta P, Hermenegildo C, Cano A, García-Pérez MA

A C >T polymorphism located at position -1 of the Kozak sequence of CD40 gene is associated with low bone mass in Spanish postmenopausal women.

Osteoporos Int. 2008 Aug;19(8):1147-52, PMID: 18097708

This study evaluated the association of a polymorphism in the CD40 gene with BMD and risk of osteopenia or osteoporosis in a population of 602 postmenopausal women. Results showed that women with the TT genotype had lower BMD at femoral neck and spine sites and increased risk of osteopenia or osteoporosis.

ENDOCRINOLOGY & METABOLISM