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Aibar J, Castro P, Espinosa G, Fernández S, Hernández C, Rinaudo M, Butjosa M, Tàssies D, Reverter JC, Nicolás JM

ADAMTS-13 in Critically Ill Patients With Septic Syndromes and Noninfectious Systemic Inflammatory Response Syndrome.

Shock. 2015 Jun;43(6):556-62, PMID: 25643015

Decreased ADAMTS-13 (A Disintegrin and Metalloprotease with a ThromboSpondin type 1 motif, member 13) seems to be associated with a poor prognosis in sepsis. However, its role in different septic syndromes and other causes of systemic inflammatory response syndrome (SIRS) remains unclear. The aims of this study were to assess ADAMTS-13 levels in patients with septic syndromes or noninfectious SIRS and to determine their association with morbidity and mortality.

HEMATOLOGY