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Núñez J, Rabinovich GA, Sandino J, Mainar L, Palau P, Santas E, Villanueva MP, Núñez E, Bodí V, Chorro FJ, Miñana G, Sanchis J

Prognostic value of the interaction between galectin-3 and antigen carbohydrate 125 in acute heart failure.

PLoS ONE. 2015;10(4):e0122360, PMID: 25875367

Galectin-3 (Gal-3) and carbohydrate antigen 125 (CA125) have emerged as robust prognostic biomarkers in heart failure. Experimental data have also suggested a potential molecular interaction between CA125 and Gal-3; however, the biological and clinical relevance of this interaction is still uncertain. We sought to evaluate, in patients admitted for acute heart failure, the association between plasma Gal-3 with all-cause mortality and the risk for rehospitalizations among high and low levels of CA125.


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