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Echavarria-Pinto M, Gonzalo N, Ibáñez B, Petraco R, Jiménez-Quevedo P, Sen S, Nijjer S, Tarkin J, Alfonso F, Núñez-Gil IJ, Bañuelos C, Quirós A, Fernández-Ortiz A, Macaya C, Koo BK, Davies J, Escaned J

Low coronary microcirculatory resistance associated with profound hypotension during intravenous adenosine infusion: implications for the functional assessment of coronary stenoses.

Circ Cardiovasc Interv. 2014 Feb;7(1):35-42, PMID: 24399244

Intravenous adenosine infusion produces coronary and systemic vasodilatation, generally leading to systemic hypotension. However, adenosine-induced hypotension during stable hyperemia is heterogeneous, and its relevance to coronary stenoses assessment with fractional flow reserve (FFR) remains largely unknown.

CARDIAC & CARDIOVASCULAR SYSTEMS