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Hernández MR, Urban P, Casals E, Estelrich J, Escolar G, Galán AM

Liposomes bearing fibrinogen could potentially interfere with platelet interaction and procoagulant activity.

Int J Nanomedicine. 2012;7:2339-47, PMID: 22654514

The contribution of fibrinogen (FBN) to hemostasis acting on platelet aggregation and clot formation is well established. It has been suggested that FBN-coated liposomes could be useful in restoring hemostasis. In the present study, we evaluated the modifications induced by multilamellar raw liposomes (MLV) or fibrinogen-coated liposomes (MLV-FBN) on hemostatic parameters.


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