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González de la Fuente M, Barana A, Gómez R, Amorós I, Dolz-Gaitón P, Sacristán S, Atienza F, Pita A, Pinto A, Fernández-Avilés F, Caballero R, Tamargo J, Delpón E

Chronic atrial fibrillation up-regulates β1-Adrenoceptors affecting repolarizing currents and action potential duration.

Cardiovasc. Res.. 2013 Feb;97(2):379-88, PMID: 23060133

β-adrenergic stimulation has profound influence in the genesis and maintenance of atrial fibrillation (AF). However, the effects of β-Adrenoceptor stimulation on repolarizing currents and action potential (AP) characteristics in human atrial myocytes from left (LAA) and right atrial appendages (RAA) obtained from sinus rhythm (SR) and chronic atrial fibrillation (CAF) patients have not been compared yet.

CARDIAC & CARDIOVASCULAR SYSTEMS

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