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Morillas P, Quiles J, de Andrade H, Castillo J, Tarazón E, Roselló E, Portolés M, Rivera M, Bertomeu-Martínez V

Circulating biomarkers of collagen metabolism in arterial hypertension: relevance of target organ damage.

J. Hypertens.. 2013 Aug;31(8):1611-7, PMID: 23615327

Increasing experimental evidence indicates that alterations in the extracellular matrix are implicated in hypertension and its chronic complications. Selected markers of extracellular matrix metabolism were investigated as potential biomarkers for hypertensive remodelling and correlated with the severity and extent of target organ damage (TOD) in patients with essential hypertension.

PERIPHERAL VASCULAR DISEASE