Freixa X, Heras M, Ortiz JT, Argiró S, Guasch E, Doltra A, Jiménez M, Betriu A, Masotti M
Rev Esp Cardiol. 2011 Feb;64(2):105-10, PMID: 21208707
High endothelin-1 (ET-1) levels have been linked to poor clinical outcomes after ST-segment elevation myocardial infarction (STEMI). Vasoconstriction of the coronary microcirculation seems to be the underlying mechanism. The aim of the study was to assess the effect of ET-1 on microvascular integrity, infarct size, left ventricular ejection fraction (LVEF) and myocardial salvage in evolving myocardial infarction (MI).
CARDIAC & CARDIOVASCULAR SYSTEMS