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Lluís-Ganella C, Subirana I, Lucas G, Tomás M, Muñoz D, Sentí M, Salas E, Sala J, Ramos R, Ordovas JM, Marrugat J, Elosua R

Assessment of the value of a genetic risk score in improving the estimation of coronary risk.

Atherosclerosis. 2012 Jun;222(2):456-63, PMID: 22521901

The American Heart Association has established criteria for the evaluation of novel markers of cardiovascular risk. In accordance with these criteria, we assessed the association between a multi-locus genetic risk score (GRS) and incident coronary heart disease (CHD), and evaluated whether this GRS improves the predictive capacity of the Framingham risk function.

PERIPHERAL VASCULAR DISEASE

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