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Núñez J, Sanchis J, Núñez E, Fonarow GC, Bodí V, Bertomeu-González V, Miñana G, Palau P, Fácila L, Chorro FJ, Bertomeu-Martínez V, Llàcer A

[Benefits of statin therapy based on plasma carbohydrate antigen 125 values following an admission for acute heart failure].

Rev Esp Cardiol. 2011 Dec;64(12):1100-8, PMID: 21958731

The prognostic benefit of statins in patients with heart failure is a topic of controversy. Under the hypothesis that statins may provide greater benefit in a subgroup of patients with heightened inflammatory activity, we sought to explore whether statins are associated with a decreased risk of long-term mortality in patients with acute heart failure based on elevated levels of carbohydrate antigen 125, a biomarker related to systemic congestion and proinflammatory status.

CARDIAC & CARDIOVASCULAR SYSTEMS