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Núñez J, Sanchis J, Bodí V, Núñez E, Heatta AM, Miñana G, Merlos P, Rumiz E, Palau P, Sanjuán R, Blasco ML, Llàcer A

Therapeutic implications of low lymphocyte count in non-ST segment elevation acute coronary syndromes.

Eur. J. Intern. Med.. 2009 Dec;20(8):768-74, PMID: 19892306

Low lymphocyte count (LLC), a surrogate for inflammation, has emerged as a potential risk factor for cardiovascular outcomes, especially new ischemic events. To identify patients with non-ST segment elevation acute coronary syndromes (NSTEACS) who benefit from an invasive revascularization strategy remains a challenge. We sought to determine if patients with high-risk NSTEACS who exhibited LLC have a greater reduction in long-term post-discharge myocardial infarction (MI) when managed under a revascularization invasive strategy (RIS) as compared with conservative strategy (CS).

MEDICINE, GENERAL & INTERNAL