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Rigol M, Heras M, Solanes N, Epelde F, Roig E, Pérez-Villa F, Roqué M, Sanz G

Enalaprilat, losartan and LU 135252 in coronary blood flow regulation.

Eur. J. Clin. Invest.. 2003 May;33(5):363-9, PMID: 12713448

High plasma levels of angiotensin II are found in several pathologies such as hypertension, heart failure and myocardial infarction. The effect of high concentrations of angiotensin II on coronary circulation is not well defined. The aim of the present study was to assess coronary blood flow regulation during tachycardia in the presence of elevated coronary plasma levels of angiotensin II, and the changes induced by ACE inhibition and blockade of angiotensin II and endothelin-A receptors.

MEDICINE, GENERAL & INTERNAL