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Echavarria-Pinto M, Petraco R, van de Hoef TP, Gonzalo N, Nijjer S, Tarkin JM, Ibanez B, Sen S, Jiménez-Quevedo P, Nunez-Gil IJ, Nombela-Franco L, Alfonso F, Fernández-Ortiz A, Macaya C, Piek JJ, Davies J, Escaned J

Fractional flow reserve and minimum Pd/Pa ratio during intravenous adenosine infusion: very similar but not always the same.

EuroIntervention. 2016 Jan;11(9):1013-9, PMID: 25366652

Maximum and stable hyperaemia are critical prerequisites for the accurate measurement of fractional flow reserve (FFR). However, in some patients in whom hyperaemia is induced through a central vein (IV) the minimum distal coronary pressure to aortic pressure ratio (Pd/Pa ratio) develops before the stabilisation of hyperaemia. We sought to describe the prevalence, magnitude and clinical implications of this phenomenon.

CARDIAC & CARDIOVASCULAR SYSTEMS