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Li Bassi G, Martí JD, Saucedo L, Rigol M, Roca I, Cabanas M, Muñoz L, Ranzani OT, Giunta V, Luque N, Esperatti M, Gabarrus A, Fernández L, Rinaudo M, Ferrer M, Ramírez J, Vila J, Torres A

Gravity predominates over ventilatory pattern in the prevention of ventilator-associated pneumonia.

Crit. Care Med.. 2014 Sep;42(9):e620-7, PMID: 24979484

In the semirecumbent position, gravity-dependent dissemination of pathogens has been implicated in the pathogenesis of ventilator-associated pneumonia. We compared the preventive effects of a ventilatory strategy, aimed at decreasing pulmonary aspiration and enhancing mucus clearance versus the Trendelenburg position.

CRITICAL CARE MEDICINE