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Cervera C, Castañeda X, de la Maria CG, del Rio A, Moreno A, Soy D, Pericàs JM, Falces C, Armero Y, Almela M, Ninot S, Paré JC, Mestres CA, Gatell JM, Marco F, Miró JM

Effect of vancomycin minimal inhibitory concentration on the outcome of methicillin-susceptible Staphylococcus aureus endocarditis.

Clin. Infect. Dis.. 2014 Jun;58(12):1668-75, PMID: 24647021

Staphylococcus aureus endocarditis has a high mortality rate. Vancomycin minimum inhibitory concentration (MIC) has been shown to affect the outcome of methicillin-resistant S. aureus bacteremia, and recent data point to a similar effect on methicillin-susceptible S. aureus bacteremia. We aimed to evaluate the effect of vancomycin MIC on left-sided S. aureus infective endocarditis (IE) treated with cloxacillin.

IMMUNOLOGY

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Ministerio de Economía y Competitividad Fondo Europeo de Desarrollo Regional IMIM - Parc de Salut Mar