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López-Farré AJ, Rodríguez-Sierra P, Modrego J, Segura A, Martín-Palacios N, Saiz AM, Zamorano-León JJ, Duarte J, Serrano J, Moñux G

Effects of factor Xa on the expression of proteins in femoral arteries from type 2 diabetic patients.

Br J Clin Pharmacol. 2014 Dec;78(6):1366-77, PMID: 25041869

Further to its pivotal role in haemostasis, factor Xa (FXa) promotes effects on the vascular wall. The purpose of the study was to evaluate if FXa modifies the expression level of energy metabolism and oxidative stress-related proteins in femoral arteries obtained from type 2 diabetic patients with end-stage vasculopathy.

PHARMACOLOGY & PHARMACY

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