Rigol M, Solanes N, Roura S, Roqué M, Novensá L, Dantas AP, Martorell J, Sitges M, Ramírez J, Bayés-Genís A, Heras M
Eur. J. Clin. Invest.. 2014 Jan;44(1):83-92, PMID: 24350923
Stem cell therapy offers a promising approach to reduce the long-term mortality rate associated with heart failure after acute myocardial infarction (AMI). To date, in vivo translational studies have not yet fully studied the immune response to allogeneic adipose tissue-derived mesenchymal stem cells (ATMSCs). We analysed the immune response and the histological and functional effects of allogeneic ATMSCs in a porcine model of reperfused AMI and determine the effect of administration timing.
MEDICINE, GENERAL & INTERNAL