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Pineda B, Hermenegildo C, Tarín JJ, Cano A, García-Pérez MA

Effects of administration of hormone therapy or raloxifene on the immune system and on biochemical markers of bone remodeling.

Menopause. 2012 Mar;19(3):319-27, PMID: 22067277

Over the last few years, conclusive evidence of the involvement of the immune system in the regulation of bone metabolism has been identified. Consequently, one question that should be formulated concerns the possible effects of antiresorptive therapies on the immune system. Therefore, the purpose of the present work was to evaluate both the functionality of the immune system and bone turnover in women receiving antiresorptive therapies, such as hormone therapy (HT; n = 33) and raloxifene (RLX; n = 66), acting through estrogen receptors.

OBSTETRICS & GYNECOLOGY